alpha-[[[2-(2-chloro-3,4-dimethoxyphenyl)ethyl]amino]methyl]-4-methoxybenzyl alcohol - Names and Identifiers
Name | N-[2-Hydroxy-2(4-methoxyphenyl)ethyl]-2-(2-chloro-3,4-dimethoxyphenyl)ethylamine
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Synonyms | Fenoldopam intermediate 2-(2-chloro-3,4-dimethoxyphenethylamino)-1-(4-methoxyphenyl)ethanol 2-{[2-(2-chloro-3,4-dimethoxyphenyl)ethyl]amino}-1-(4-methoxyphenyl)ethanol N-[2-Hydroxy-2-(4-Methoxyphenyl)Ethyl]-2-(2-Chloro-3,4-Dimethoxyphenyl)Ethylam N-[2-Hydroxy-2-(4-methoxyphenyl)ethyl]-2-(2-chloro-3,4-dimethoxy phenyl)ethylami N-[2-Hydroxy-2-(4-Methoxyphenyl)Ethyl]-2-(2-Chloro-3,4-Dimethoxyphenyl)Ethylamin N-[2-Hydroxy-2(4-methoxyphenyl)ethyl]-2-(2-chloro-3,4-dimethoxyphenyl)ethylamine α-[[[2-(2-Chloro-3,4-dimethoxyphenyl)ethyl]amino]methyl]-4-methoxybenzenemethanol N-[2-HYDROXY-2-(4-METHOXYPHENYL)ETHYL]-2-(2-CHLORO-3,4-DIMETHOXYPHENYL)ETHYLAMINE alpha-[[[2-(2-chloro-3,4-dimethoxyphenyl)ethyl]amino]methyl]-4-methoxybenzyl alcohol alpha-[[[2-(2-Chloro-3,4-dimethoxyphenyl)ethyl]amino]methyl]-4-methoxy-benzenemethanol
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CAS | 71636-38-9
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EINECS | 275-740-2 |
InChI | InChI=1/C19H24ClNO4/c1-23-15-7-4-13(5-8-15)16(22)12-21-11-10-14-6-9-17(24-2)19(25-3)18(14)20/h4-9,16,21-22H,10-12H2,1-3H3 |
alpha-[[[2-(2-chloro-3,4-dimethoxyphenyl)ethyl]amino]methyl]-4-methoxybenzyl alcohol - Physico-chemical Properties
Molecular Formula | C19H24ClNO4
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Molar Mass | 365.85 |
Density | 1.191 |
Melting Point | 118-121°C |
Boling Point | 526°C at 760 mmHg |
Flash Point | 271.9°C |
Vapor Presure | 6.82E-12mmHg at 25°C |
Storage Condition | 2-8°C(protect from light) |
Refractive Index | 1.562 |
alpha-[[[2-(2-chloro-3,4-dimethoxyphenyl)ethyl]amino]methyl]-4-methoxybenzyl alcohol - Introduction
N-[2-Hydroxy-2(4-methoxyphenyl)ethyl]-2-(2-chroo-3, 4-dimethoxyphenyl)ethylamine is an organic compound with the formula C19H24ClNO3. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
1. appearance: white to light yellow crystal or crystalline powder.
2. solubility: soluble in alcohol, ether and some organic solvents, insoluble in water.
3. Melting point: about 112-114°C.
Use:
N-[2-Hydroxy-2(4-methoxyphenyl)ethyl]-2-(2-chroo-3, 4-dimethoxyphenyl)ethylamine is commonly used in the field of medicine and as an intermediate for anti-cancer drugs or anti-tumor drugs. It has the ability to bind to hormone receptors and helps regulate cell proliferation and apoptosis.
Preparation Method:
The following is a common preparation method:
Reaction of 4-methoxybenzyl alcohol with 2-bromoacetate yields 2-(4-methoxyphenyl) acetate. This is followed by reaction with 2-(4-methoxyphenyl) acetate under basic conditions using a specific amide reagent to yield the N-[2-Hydroxy-2(4-methoxyphenyl)ethyl]-2-(2-chroo-3, 4-dimethoxyphenyl)ethylamine.
Safety Information:
1. N-[2-Hydroxy-2(4-methoxyphenyl)ethyl]-2-(2-choro-3, 4-dimethoxyphenyl)ethylamine should pay attention to explosion-proof and fire-proof measures during use.
2. Wear appropriate personal protective equipment such as lab gloves and goggles when in contact with this compound.
3. When using or handling the compound, please ensure that the operation is carried out in a well-ventilated environment to avoid inhalation or skin contact.
4. Please store and handle the compound properly, and follow the relevant safety procedures and regulations. When disposing of waste, please comply with local environmental regulations and adopt appropriate purification and disposal methods.
Last Update:2024-04-09 19:05:51